MyBioSource.com's Acetyl-Histone H4 (Lys5) Rabbit mAb is a Rabbit monoclonal antibody. The Acetyl-Histone H4 (Lys5) Rabbit mAb Antibody was generated using H4 clustered histone 15, H4 clustered histone 8, H4 histone 16, H4-16, H4C15, and H4C8 as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures